2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-17596A
    Closantel sodium
    		Inhibitor 99.76%
    Closantel sodium is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel sodium is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel sodium inhibits the O. volvulus L3 to L4 molt of developing.
    Closantel sodium
  • HY-145079
    Bunamidine hydrochloride
    		99.79%
    Bunamidine hydrochloride is a veterinary anti-platyhelmintic agent used for Echinococcus granulosus and Taenia hydatigena.
    Bunamidine hydrochloride
  • HY-B0744D
    L-Eflornithine monohydrochloride
    		≥98.0%
    L-Eflornithine monohydrochloride (L-DFMO monohydrochloride) is an enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1.3±0.3 µM, and a Kinact of 0.15±0.03 min-1.
    L-Eflornithine monohydrochloride
  • HY-B1934
    Methyl stearate
    		Inhibitor 99.31%
    Methyl stearate, isolated from Rheum palmatum L. is a compopent of of soybean and rapeseed biodiesels.
    Methyl stearate
  • HY-N6009
    8-Deoxygartanin
    		Inhibitor 99.24%
    8-Deoxygartanin, a prenylated xanthones from G. mangostana, is a selective inhibitor of butyrylcholinesterase (BChE). 8-Deoxygartanin exhibits antiplasmodial activity with an IC50 of 11.8 μM for the W2 strain of Plasmodium falciparum. 8-Deoxygartanin inhibits NF-κB (p65) activation with an IC50 of 11.3 μM.
    8-Deoxygartanin
  • HY-41656
    D-Praziquanamine
    		Control
    D-Praziquanamine is the isomer of L-Praziquanamine (HY-N1765), and can be used as an experimental control. L-Praziquanamine is a natural product.
    D-Praziquanamine
  • HY-W749694
    Cannflavin B
    		Inhibitor 98.36%
    Cannflavin B is a flavonoid compound that can be isolated from Cannabis sativa L. Cannflavin B is inhibitors of PGE2 release (IC50: 0.7 μM), mPGES-1 (IC50: 3.7 μM), and 5-lipoxygenase. Cannflavin B has multiple activities such as anti-inflammatory, antioxidant, anti-glycation, anti-ferroptosis, anti-tumor, and anti-Leishmania (IC50: 14 μM). Cannflavin B can also inhibit the TrkB-BDNF signaling pathway.
    Cannflavin B
  • HY-136394
    Diafenthiuron
    		Inhibitor 98.29%
    Diafenthiuron is a thiourea compound commonly used a broad-spectrum insecticide and acaricide. Diafenthiuron disturbs the insect respiratory system by inhibiting the oxidative phosphorylation and mitochondrial ATP synthesis.
    Diafenthiuron
  • HY-12779
    Cyantraniliprole
    		Inhibitor 99.60%
    Cyantraniliprole (HGW-86) is a potent and selective aniline receptor activator with oral activity. Cyantraniliprole has insecticidal and antioxidant activity.
    Cyantraniliprole
  • HY-117025A
    Manzamine A hydrochloride
    		Inhibitor 99.66%
    Manzamine A hydrochloride, an orally active beta-carboline alkaloid, inhibits specifically GSK-3β and CDK-5 with IC50s of 10.2 μM and 1.5 μM, respectively. Manzamine A hydrochloride targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. Manzamine A hydrochloride has antimalarial and anticancer activities. Manzamine A hydrochloride also shows potent activity against HSV-1.
    Manzamine A hydrochloride
  • HY-136429A
    Ethylhydrocupreine hydrochloride
    		Inhibitor 99.72%
    Ethylhydrocupreine hydrochloride (Optochin hydrochloride) is a quinine derivate with antimicrobial activity against S. pneumoniae. Ethylhydrocupreine hydrochloride also possesses antimalarial activity against Plasmodium falciparum, with an IC50 of 25.75 nM. Ethylhydrocupreine hydrochloride is a Gallus gallus taste 2 receptors (ggTas2r1, ggTas2r2 and ggTas2r7) agonist.
    Ethylhydrocupreine hydrochloride
  • HY-B0740
    Cyclobenzaprine hydrochloride
    		Inhibitor 99.59%
    Cyclobenzaprine (MK130) hydrochloride is an orally active 5-HT2 receptor antagonist. Cyclobenzaprine hydrochloride acts centrally, providing skeletal muscle relaxation, alleviating muscle spasms, and reducing pain. Additionally, Cyclobenzaprine hydrochloride has antiprotozoal activity. Additionally, Cyclobenzaprine hydrochloride also possesses antiparasitic activity. Cyclobenzaprine hydrochloride holds promise for research in the fields of acute, painful skeletal muscle disorders and infectious diseases
    Cyclobenzaprine hydrochloride
  • HY-B1113
    Diazinon
    		Inhibitor 99.25%
    Diazinon is an orally active, irreversible AChE inhibitor and insecticide that can be absorbed through the digestive system, skin or respiratory tract. Diazinon inhibits AChE, leading to accumulation of acetylcholine, which in turn overstimulates ACh receptors and affects the nervous system. Diazinon also produces reactive oxygen species (ROS)， which induce oxidative stress in various tissues. Diazinon is mainly used in the agricultural field as an insecticide and may have potential effects on human and animal health.
    Diazinon
  • HY-N7906
    Myricetin 3-O-glucoside
    		Inhibitor ≥99.0%
    Myricetin 3-O-glucoside (Myricetin 3-β-D-glucopyranoside) is a flavonol from Tibouchina paratropica and Hakmeitau beans. Myricetin 3-O-glucoside exhibits anti-Leishmanial, anti-inflammatory and antimicrobial activities.
    Myricetin 3-O-glucoside
  • HY-136450
    Triclabendazole sulfoxide
    		Inhibitor 98.78%
    Triclabendazole sulfoxide (TCBZ-SO) is the main plasma metabolite of Triclabendazole, and exhibits anti-parasite effects. Triclabendazole sulfoxide can inhibit membrane transporter ABCG2/BCRP.
    Triclabendazole sulfoxide
  • HY-N2384A
    Febrifugine dihydrochloride
    		Inhibitor 99.95%
    Febrifugine dihydrochloride is a quinazolinone alkaloid that inhibits P. falciparum and has antimalarial activity. Febrifugine dihydrochloride inhibits bladder cancer by inhibiting DNA synthesis, inducing apoptosis, and reducing steroids.
    Febrifugine dihydrochloride
  • HY-B1094
    Aklomide
    		Inhibitor ≥98.0%
    Aklomide (2-Chloro-4-nitrobenzamide) is a coccidiostat agent. Aklomide can be used for the prevention and control of coccidiosis in chickens.
    Aklomide
  • HY-B0825
    (E)-Fenpyroximate
    		Inhibitor 99.81%
    (E)-Fenpyroximate is a potent acaricide.
    (E)-Fenpyroximate
  • HY-B0826
    Spirodiclofen
    		Inhibitor 99.93%
    Spirodiclofen (BAJ-2740) is a broad spectrum acaricide acting via lipid biosynthesis inhibition (LBI) with no cross resistance to currently available acaricides and with additional insecticidal properties.
    Spirodiclofen
  • HY-10852
    Arterolane
    		Inhibitor ≥98.0%
    Arterolane is an antimalarial agent, with IC50 of both 1.1 nM against P. falciparum Ro73 and W2, respectively.
    Arterolane
Parasite Isoform Comparison

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