2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-118494
    Ascaridole
    		Inhibitor 98.65%
    Ascaridole is an anthelmintic and also has antimalarial activity.
    Ascaridole
  • HY-114489A
    Haemanthamine
    		Inhibitor
    Haemanthamine is a crinine-type alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. Haemanthamine targets ribosomal that inhibits protein biosynthesis during the elongation stage of translation. Haemanthamine has pro-apoptotic, antioxidant, antiviral, antimalarial and anticonvulsant activities.
    Haemanthamine
  • HY-19502
    Artemisone
    		Inhibitor ≥98.0%
    Artemisone (Artemifone) is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains, with a mean IC50 of 0.83 nM. Artemisone is also a potent inhibitor of human CMV.
    Artemisone
  • HY-105117
    Fantofarone
    		Inhibitor 99.91%
    Fantofarone is a highly potent Calcium Channel antagonist.
    Fantofarone
  • HY-P2310A
    Defensin HNP-1 human TFA
    		Inhibitor 99.91%
    Defensin HNP-1 human TFA is a Human neutrophil peptides (HNPs), involved in endothelial cell dysfunction at the time of early atherosclerotic development. Defensin HNP-1 human TFA exhibits broad antimicrobial and anti-leishmanial activities.
    Defensin HNP-1 human TFA
  • HY-115584
    Lufenuron
    		Inhibitor 99.57%
    Lufenuron is an orally active lipophilic benzoylurea insecticide and a chitin synthesis inhibitor that can used for flea and fish lice control. Lufenuron inhibits moulting of arthropods. Lufenuron induces reproductive toxicity, genotoxic effects and oxidative stresses in pregnant albino rats and their fetuses.
    Lufenuron
  • HY-N7906
    Myricetin 3-O-glucoside
    		Inhibitor ≥99.0%
    Myricetin 3-O-glucoside (Myricetin 3-β-D-glucopyranoside) is a flavonol from Tibouchina paratropica and Hakmeitau beans. Myricetin 3-O-glucoside exhibits anti-Leishmanial, anti-inflammatory and antimicrobial activities.
    Myricetin 3-O-glucoside
  • HY-135652
    Hexyl gallate
    		Inhibitor 99.75%
    Hexyl gallates (Hexyl 3,4,5-trihydroxybenzoate) shows antibacterial activity and inhibits the production of rhamnolipid and pyocyanin by inhibiting RhlR. Hexyl gallate, a alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum, with IC50 of 0.11 mM.
    Hexyl gallate
  • HY-12607
    ML251
    		Inhibitor 99.62%
    ML251, a potent nanomolar T. brucei and T. cruzi phosphofructokinase (PFK) inhibitor, inhibits T. brucei PFK (IC50=0.37 μM) and T. cruzi PFK (IC50=0.13 μM). ML251 can be used for the research of parasite.
    ML251
  • HY-B0826
    Spirodiclofen
    		Inhibitor 99.93%
    Spirodiclofen is a broad spectrum acaricide acting via lipid biosynthesis inhibition (LBI) with no cross resistance to currently available acaricides and with additional insecticidal properties.
    Spirodiclofen
  • HY-18748
    BQR-695
    		Inhibitor 99.92%
    BQR-695 is a PI4KIIIβ inhibitor with IC50s of 80 and 3.5 nM for human PI4KIIIβ and Plasmodium variant of PI4KIIIβ, respectively.
    BQR-695
  • HY-12785
    Albendazole sulfoxide
    		Inhibitor 99.20%
    Albendazole sulfoxide (Ricobendazole), the main active metabolite of Albendazole, exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes.
    Albendazole sulfoxide
  • HY-117684A
    Cabamiquine succinate
    		Inhibitor 99.80%
    Cabamiquine (DDD107498) succinate is a potent and orally active antimalarial agent, inhibits multiple life-cycle stages of the parasite, with an EC50 of 1 nM against P. falciparum 3D7. Cabamiquine succinate inhibits protein synthesis by targeting eEF2/CaMKIII, with an EC50 of 2 nM for WT-PfeEF2.
    Cabamiquine succinate
  • HY-N0337S
    Eugenol-d3
    		Inhibitor 99.86%
    Eugenol-d3 is the deuterium labeled Eugenol. Eugenol is an essential oil found in cloves with antibacterial, anthelmintic and antioxidant activity. Eugenol is shown to inhibit lipid peroxidation.
    Eugenol-d<sub>3</sub>
  • HY-P3512
    Iseganan
    		Inhibitor
    Iseganan is an anti-microbial peptide that is active against both Gram-positive and Gram-negative bacteria and fungi. Iseganan kills a broad-spectrum of bacteria and fungi by attaching to and destroying the integrity of the lipid cell membranes. Iseganan can be used for oral mucositis research.
    Iseganan
  • HY-119931
    2-Hydroxychalcone
    		98.80%
    2-hydroxychalcone, a natural flavonoid, is a potent antioxidant, inhibiting lipid peroxidation. 2-Hydroxychalcone induces apoptosis by Bcl-2 downregulation. 2-Hydroxychalcone inhibits the activation of NF-kB.
    2-Hydroxychalcone
  • HY-118607
    VU041
    		Inhibitor 99.31%
    VU041 is a first submicromolar-affinity inhibitor of Anopheles (An.) gambiae and Aedes (Ae.) aegypti inward rectifier potassium 1 (Kir1) channels with IC50 values of 2.5 μM and 1.7 μM, respectively. VU041 inhibits appreciably is mammalian Kir2.1 (IC50 of 12.7 μM), and has less inhibitory effect on mammalian Kir1.1, Kir4.1, Kir6.2/SUR1, and Kir7.1. VU041 also induces impaired Malpighian tubule function.
    VU041
  • HY-B0846
    Dimethomorph
    		99.13%
    Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 µM.
    Dimethomorph
  • HY-B0744D
    L-Eflornithine monohydrochloride
    		≥98.0%
    L-Eflornithine monohydrochloride (L-DFMO monohydrochloride) is an enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1.3±0.3 µM, and a Kinact of 0.15±0.03 min-1.
    L-Eflornithine monohydrochloride
  • HY-117015
    Purfalcamine
    		Inhibitor 99.44%
    Purfalcamine is an orally active, selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with an IC50 of 17 nM and an EC50 of 230 nM. Purfalcamine has antimalarial activity and causes malaria parasites developmental arrest at the schizont stage.
    Purfalcamine
Parasite Isoform Comparison

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